Biochemistry

4611-CHU-Unilab Lg-logoWe have developed particular competences in several very specialized topics like bone and cartilage markers, in vitro allergology, oxidative stress, hormonology and endocrinology, cardiac markers and auto-immunity. We also have validated different methods for 25(OH) vitamin D determination.

Our services include:

  • A complete panel of chemistry analyses including (but not exclusively) electrolytes, hormones, peptides, cytokines, specialized oxidative stress markers (lipid peroxidation, ROS assays, anti-oxidant assays, fatty acids determination), growth factors, lipids, enzymes…
  • Biochemical characterization of your samples including patient blood samples, culture media…

Contact [info@b2h.be] us to discuss how these capabilities can forward your projects! We will help you develop tailored solutions.

Microbiology

MicrobiologyThe clinical microbiology laboratory is a full-service routine and specialized reference laboratory. They test diverse specimens from patients to detect a wide range of human pathogens that are, or may be, a cause of the illness. Their role is also to provide information about the in vitro activity of antimicrobial drug against the microorganisms identified.

Each year, researchers perform about:

  • 350.000 cultures or analyses from more or less 130.000 clinical specimens
  • Thousands of clinical and therapeutic advices
  • 250 clinical rounds with the infectious diseases specialists of the university hospital
  • 3.000 cultures with identification for microbiological quality assessment from environmental samples

As a national reference laboratory for AIDS, Streptococcus agalactiae, Vibrio cholerae /parahaemolyticus and mycosis/fungi since 90’s, we perform epidemiological surveillances at national and international levels. The laboratory has extensive experience in developing, conducting and interpreting tests for patients with infectious diseases and for those prone to infections, such as immunocompromised, cancer and AIDS patients.

Most of our laboratories are biosafety level 2 and we established biosafety level 3 facilities for mycobacteriology and AIDS reference laboratory.

Contact [info@b2h.be] us to discuss how these capabilities can forward your projects! We will help you develop tailored solutions.

Our services include:

  • Analysis of numerous types of specimens collected from a wide variety of body sites using various diagnostic tools (e.g. microscopy, MALDI-TOF, ITS sequencing, detection of microbial antigens, growth of microorganisms in culture, detection of microbial DNA and/or RNA, and/or detection of antibodies)
  • Microbiological surveillance of environment
  • Screening/attesting antimicrobial activities of various types of products
  • Microbiological testing of your samples
  • Genotyping of dermatophytes
  • Susceptibility testing for yeasts and filamentous fungi involved in invasive infections
  • Confirmation of the infection by HIV by using serology and molecular testing
  • Determination of the viral load and genotyping
  • Tests for clinical trials for pharmaceutical companies and/or academic researchers
  • Additional services: reference-level organism identification, support to infection prevention and control programs, research, education and clinicala consultation

Toxicology

ToxicologyUnilab has established a clear leadership in all fields of human toxicology such as clinical, forensic, industrial and environmental toxicology. Our medical subspecialty focuses on the diagnosis, management and prevention of poisoning and other adverse health effects due to medications, occupational and environmental toxicants.

We realize each year more or less:

  • 40.000 clinical analyses (serum or urine)
  • 500 forensic expertise
  • 25 environmental assessments
  • 200 to 300 industrial analyses

 

  • Therapeutic drug monitoring (measure of ex vivo blood concentration of the drugs): we can assist you with the development and validation of multiple separation methods to perform drug monitoring (parent drugs or metabolites) in various sample matrices including blood, urine, hair, breast milk and tissues
  • Diagnosis of acute or chronic intoxication: identification and quantification in biological samples of drugs, narcotics or toxic products of another nature. The laboratory has developed varied techniques, immunological and chromatographic methods, allowing a fast description of the principal poisons responsible for acute pathologies

Contact [info@b2h.be] us to discuss how these capabilities can forward your projects! We will help you develop tailored solutions.

  • Study of the opiates pharmacokinetic within the framework of drug withdrawal
  • Development of different analytical methods to confirm drugs consumption with unconventional matrix such as scalp hair or saliva (BELAC accreditation for unconventional matrix)

Contact [info@b2h.be] us to discuss how these capabilities can forward your projects! We will help you develop tailored solutions.

  • Evaluation of toxic risks for human exposed to various endocrine disturbers (pesticides and drugs such as hormones, plastifyers or conservant)
  • Study of the influence of the oxidative stress on the metabolism and the folate transport in autistics patients
  • Determination of threshold values for polluant in air
  • Determination of acute toxicity threshold to be used in case of major accidents

Contact [info@b2h.be] us to discuss how these capabilities can forward your projects! We will help you develop tailored solutions.

  • Comet assay to evaluate DNA damages, a rapid and sensitive method. This test is used as early genotoxicity screening of chemical entities
  • Markers of genetic susceptibility in industrial toxicology

In addition, we can also develop new analytical methods for the determination and reliable quantification of a wide range of small organic molecules (ranging from 100 to 600 Da), whether volatile, semi-volatile, non-volatile or thermo labile, as long as the compound is available as a standard.

Furthermore, we are experienced in the establishment of pharmacokinetic profiles.

Overall, we are capable of the design, set up and validation of new methods dedicated to your needs.

Contact [info@b2h.be] us to discuss how these capabilities can forward your projects! We will help you develop tailored solutions.


Haematology

ImmunohematologyWe harbor the largest blood bank in Wallonia and our histocompatibility and immunogenetics unit is accredited by the European Federation for Immunogenetics and Eurotransplant for solid organ and stem cell transplants.

Our services include:

  • Complete blood counts and leukocyte differentials using the latest technology in blood cell counters equipped with digital microscopy
  • Cytology of body fluid through automated counters and microscopy
  • Immunophenotyping analysis of lymphocyte subpopulations, blood cell precursors and qualification of haematopoietic and non-haematopoietic stem cell products
  • Broad coagulation screens
  • Specialized tests for deficiencies in pro-coagulant and anticoagulant factors
  • Von Willebrand disease testing
  • Assessment of acquired inhibitors and lupus anticoagulants
  • Fibrinolysis evaluation
  • Thrombin generation assays
  • Blood grouping and serologic testing
  • Serologic testing for anti-HLA antibodies by complement-dependent cytotoxicity and bead array
  • HLA typing by serology and molecular biology (by SSO and SSP techniques)

Contact [info@b2h.be] us to discuss how these capabilities can forward your projects! We will help you develop tailored solutions.