Mass Spectrometry
Using state-of-the-art equipment, researchers of ULg provide innovative solutions in the fields of: Analytical chemistry (volatile and non-volatile small organic compound analysis…) Medical chemistry (toxicology analysis in biological fluids, identification and quantification of new biomarkers, biomarker signature validation…) Biological and pharmaceutical chemistry (biomolecule full characterization, pharmaceutical interaction with protein or DNA target, quantification of metabolites of […]
Laser capture microdissection
Tissue microdissection or laser capture microdissection (LCM) is an automated sample preparation technique enabling the isolation of specific cells from heterogeneous materials under microscopic visualization. LCM is contact-free, thanks to the specimen collection by gravity, which helps to minimize contamination. This precise technique allows the selective analysis of specific regions, down to single cells and the extraction […]
Proteomics
Our Proteomic GIGA platform is at the forefront of technological innovation and assay development. The facility is hosted by the Mass Spectrometry Laboratory and works in collaboration with the Center for Analytical Research and Technology. It offers expert services in proteins characterization (sequencing, post-translational modifications, heterogeneity, etc) and targeted quantification (biologics, biomarkers).
Genomics/Transcriptomics
Our Genetics GIGA platform is at the forefront of technological innovation and assay development. It offers expert services in high-throughput genomic assays, including array- and NGS-based NSP genotyping, variant detection, transcriptome and epigenome analyses. In addition, the Genetic Department of the CHU has developed a large expertise in the diagnosis of genetic diseases, including genetic […]
Metabolomics
Our lab are equipped with state-of-the-art technologies to detect, separate, identify and quantify molecules covering a large chemical space. Non-target and target analyses are performed using Nuclear Magnetic Resonance (NMR) and chromatography coupled to mass spectrometry. Researchers at ULg and CHU have extensive experience working with different matrices such as blood, plasma, milk, urine, saliva, organs/tissues, cell […]