Catégorie de technologie: Protein engineering

Proteins are valuable therapeutic compounds, research reagents and industrial catalysts. The challenge is to understand the relationship between the structures of proteins and their functions, from both practical and fundamental points of view. The specificity of the multidisciplinary research center CIP is to cover the full range from gene cloning to protein production, purification and characterization.

Protein characterization

We offer biochemical and biophysical analyses to assess the purity, folding and stability of the purified sample. This includes: Biochemical characterization (enzymology, kinetics, sequencing, protein-protein interactions, proteomics, etc) Biophysical charaterization (microcalorimetry, dynamic/static light scattering, protein stability, folding & aggregation, X-ray crystallography, etc) Protein immunoquantification (Jess system) Our Robotein Platform encompasses an Octet system that allows high-throughput analyses of protein interactions in 96- […]

Protein production & purification

The protein factory platform provides many services as like: Genetic engineering (site-directed mutagenesis, random mutagenesis, protein design) and cloning in bacterial strains such as Coli, Bacillus subtilis, Bacillus amyloquefaciens, Streptomyces lividans or in yeast such as Pichia pastoris Analytical scale or pilot scale recombinant protein production in high cell density conditions Cell harvesting or supernatant cleaning using […]