Induced pluripotent stem cells
Due to the close association with the CHU de Liège, GIGA researchers have access to fibroblasts of patients. They have developed a large expertise in the generation of induced pluripotent stem cells, their characterization and differentiation into specialized neuronal cells in vitro.
Teams at GIGA are specialized in the investigations of stem cells (including mesenchymal stem cells and neural crest stem cells) biology, purification and expansion, as well as in their therapeutic use in the context of regenerative medicine.
Oxygen consumption rate
The oxygen consumption rate of different cells types can be measured and the modulating effect of molecules (natural or synthetic) on mitochondrial respiratory parameters, mitochondrial function/dysfunction can be evaluated using an Ouroboros Oxygraph-2k, a modular system for high-resolution respirometry.