Acute SCI mouse model

This model requires a contusive injury on the dorsal spinal cord using computerized device. The advantages of using this type of device is the ability to inflict reproducible injuries without touching the spinal cord before the hit.

The instrumentation senses the surface of the exposed spinal cord and continues to displace spinal tissue until it attains a predetermined force, at which point the impactor tip immediately withdraws.

The probe can also be halted at specific force levels to model extended compression injuries.

Various biomechanics parameters (i.e., velocity, force, tissue compression/displacement) can be monitored and thus animals that do not meet preset standards are eliminated early on in the study.

Contact [info@b2h.be] us to discuss how these capabilities can forward your projects! We will help you develop tailored solutions.

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